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September 02, 2010, 09:44:47 PM
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 Brand name: rosiglitazone
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The ALT elevations in patients treated with rosiglitazone were reversible. Decreases in hematologic parameters may be related to increased plasma volume observed with rosiglitazone treatment. However, in 26-week double-blind, fixed-dose studies of rosiglitazone added to insulin, edema was reported with higher frequency (rosiglitazone in combination with insulin, 14. Healthcare professionals should consider the risk of fracture when initiating or treating female patients with type 2 diabetes mellitus with rosiglitazone. Significantly more female patients who received rosiglitazone experienced fractures of the upper arm, hand, or foot, than did female patients who received either metformin or glyburide. No increase in fracture rates was observed in men treated with rosiglitazone.

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